Priscilla Lynn Macy sets off on a road trip with her two daughters and her grandparents, Mona and Poppy, hoping to clear her head and figure out what she wants out of life, and soon learns the importance of home, family, and faith.

Roxy Abruzzo, the independent-minded niece of a Pittsburgh kingpin, tries to avoid involvement in her uncle's dealings but winds up in trouble when she takes possession of an ancient Greek statue whose previous owner, the heir to a Pittsburgh steel fortune, is murdered.

The death of single mom Marty Winslow's thirteen-year-old daughter from a rare genetic disease is accompanied by the news that the child was switched at birth, and when Marty learns that her biological daughter has been orphaned, she sues for and wins custody of Andie, whose own grief and anger with God makes it even more difficult to adjust to her new family and circumstances.

Ten years after finding fame with a novel based on her own life, Cannie Shapiro has faded from the spotlight, content to write science fiction under a pen name and raise her daughter, Joy, but as Joy prepares for her bat mitzvah and begins to ask questions about Cannie's past, Cannie realizes she cannot hide forever if she wants to be truly happy.